Book review: The White Plague by Frank Herbert

(out of 5 stars)

Year published: 1982
Category: science thriller; medical thriller; psychological thriller; science fiction

Tech rating (out of 5):


A molecular biologist is driven mad when he witnesses the murder of his wife and children by Irish Republican terrorists (ah, remember those pre-9/11 days?). He takes his revenge by engineering a plague that kills women. Like the plague, Herbert’s story travels the globe, following the attempts of governments to contain or cure the disease, and the unraveling of society that accompanies the death of the female half of the world’s population.


Yes, the author is the same Frank Herbert who wrote the science fiction classic Dune. In terms of style, The White Plague has much in common with Dune. It’s moody, complex, deeply psychological, political and apocalyptic, and certainly bears little resemblance to the potato-chippy quick snacks that most contemporary thrillers are. The White Plague is long and thought-provoking, delving into morality and the meaning of insanity. It is also an exceedingly well-written story, though Herbert’s style for conveying action is sometimes obtuse.

Most of the plot takes place in Ireland, a country hard-hit as the first target of the biologist’s revenge. We follow the travails of a young couple, a (male) medical student and his nursing student girlfriend who wander the countryside trying to avoid contamination that would lead to her death. Civil war and terrible cruelty haunt their steps. Also traveling the dangerous country roads of Ireland is the perpetrator, who is mentally unhinged but the target of an intensive manhunt because only he knows how to end the holocaust he began.

Note the publication date: 1982. The single most remarkable thing about this book is the prescience Herbert shows in regard to biotechnology. At that time, genetic engineering was in its infancy; only the simplest gene splicing experiments had been performed, and few members of the general public had a clue of the growing power of the biological sciences. Frank Herbert’s imagination leaped forward a generation, postulating the creation of a disease specifically designed by a bioterrorist (before the word existed) with a molecular preference for a targeted subset of humans: females. Herbert impressed me by tossing around a variety of relevant technical terms, though ultimately the scientific details are vague and don’t hold up to scrutiny.

But technical accuracy isn’t the point. The White Plague is a compelling story that defies easy categorization: part literary fiction, part science fiction, part thriller. Definitely worth reading.

Click here to buy White Plague from amazon.

Recommended to: Dune fans who also enjoy thrillers

If you like this book, try: The Deus Machine by Pierre Ouellette

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2 Responses to Book review: The White Plague by Frank Herbert

  1. Donna Weaver says:

    I read this book many years ago, and it totally messed with my head. Nice review.

    • Amy says:

      Thanks Donna! There are some really dark, complicated characters in it. I loved the very ending, when the structure of society is so dramatically changed that polyandry (the opposite of polygamy) becomes the norm…

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